MD Shakhaowat Hossain
PhD Candidate in Biomedical Sciences
Computational Biology | Histocompatibility & Immunogenetics | AI/ML | Transplant Informatics
Center for Biomedical Informatics & Genomics · Tulane University School of Medicine
Recent Publications
Use of Intermediate-Resolution Deceased Donor Molecular Typing in Organ Allocation Systems Could Increase the Fraction of HLA-Compatible Donor Offers.
Target: American Journal of Transplantation. (2026) pre_submission
A Web-based Matchability Calculator Based on Comprehensive HLA Population Reference Data, A New Metric for Optimizing US Organ Allocation Policy.
Target: American Journal of Transplantation. (2026) pre_submission
More HLA-Matched Transplants at "Zero" Cost, Personalizing HLA Allocation Priority.
Target: American Journal of Transplantation. (2026) pre_submission
At a Glance
Current Research
Graduate Research Assistant (Dissertation) — Tulane University School of Medicine
PI: Loren Gragert, PhD (Center for Biomedical Informatics & Genomics)
Research Collaborator — Harbor-UCLA Medical Center
PI: Kristen Nordham, MD (Department of Surgery)
Research Collaborator — NYU Langone Health
PI: Michal A. Mankowski, PhD (Department of Surgery, NYU Grossman School of Medicine)
Tools & Software
HLA Matchability Calculator
Public Django web application on AWS EC2 — real-time individualized HLA matching...
Transplant Toolbox
Modernized the Gragert Lab's suite of public-facing transplant immunology tools:...
HaploFreqImpute
High-resolution HLA imputation model leveraging expectation-maximization, ~10M N...
AlleleFreqImpute
Single-locus baseline imputation pipeline; comparator to HaploFreqImpute....
Probabilistic Offer Filter
Reference implementation demonstrating automation of the UNet match-run via impu...
Clinical Typing Parsers
Three production-grade ingestion pipelines that convert heterogeneous vendor-spe...
HLA-RAG
Domain-specific retrieval-augmented generation system over ~3,500 curated HLA ar...
ILC3-RAG
Retrieval-augmented generation system built on ~2,600 curated Q1 journal article...